BDBM50195244 CHEMBL3926554::US10287258, Example 24::US10669245, Example 24::US11117874, Example 24::US11655221, Example 24::US11680049, Example 24::US20230278969, Example 24
SMILES Cn1c2cc(ccc2ccc1=O)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1
InChI Key InChIKey=BQIZWZAQEICNDG-GMAHTHKFSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50195244
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of DPP1 in human U937 cells using Gly-Phe-AFC as substrate preincubated for 60 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 13.8nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 13.8nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 13.8nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 13.8nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 13.8nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 13.8nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Charles River Discovery Research Services
Curated by ChEMBL
Charles River Discovery Research Services
Curated by ChEMBL
Affinity DataIC50: 13.8nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair