BDBM50196129 CHEMBL214996::{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-2-methylquinolin-3-yl}methanol

SMILES CC1CN(CCN1C)c1ccc(Nc2c(CO)c(C)nc3ccccc23)cc1

InChI Key InChIKey=BSEZBDDBKUJHQP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50196129   

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Timisoara Of The Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50196129(CHEMBL214996 | {4-[4-(3,4-dimethylpiperazin-1-yl)p...)
Affinity DataKi:  7.5nMAssay Description:Binding affinity to human cloned Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Timisoara Of The Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50196129(CHEMBL214996 | {4-[4-(3,4-dimethylpiperazin-1-yl)p...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2C expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196129(CHEMBL214996 | {4-[4-(3,4-dimethylpiperazin-1-yl)p...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2A expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Juvantia Pharma

Curated by ChEMBL
LigandPNGBDBM50196129(CHEMBL214996 | {4-[4-(3,4-dimethylpiperazin-1-yl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]rauwolscine from human ADRA2B expressed in S115 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed