BDBM50199503 1-(N-((1r,4r)-4-tert-butylcyclohexyl)-4-(trifluoromethoxy)benzamido)-N-(2H-tetrazol-5-yl)-2,3-dihydro-1H-indene-5-carboxamide::CHEMBL232037

SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(C1CCc2cc(ccc12)C(=O)Nc1nnn[nH]1)C(=O)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=MTBJTQZAQADZQL-JDVJWJCPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199503   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199503(1-(N-((1r,4r)-4-tert-butylcyclohexyl)-4-(trifluoro...)
Affinity DataIC50:  1.47E+3nMAssay Description:Antagonist activity at human glucagon receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199503(1-(N-((1r,4r)-4-tert-butylcyclohexyl)-4-(trifluoro...)
Affinity DataIC50:  610nMAssay Description:Antagonist activity at human GIP receptor transfected in CHO cells assessed as inhibition of glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199503(1-(N-((1r,4r)-4-tert-butylcyclohexyl)-4-(trifluoro...)
Affinity DataIC50:  49nMAssay Description:Displacement of [125]glucagon from human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed