BDBM50201365 1-methyl-4-(pyridin-4-ylmethylamino)-N-(4-(trifluoromethyl)phenyl)-1H-pyrazole-5-carboxamide::CHEMBL240455

SMILES Cn1ncc(NCc2ccncc2)c1C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=KDICQMGDECIGIR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201365   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201365(1-methyl-4-(pyridin-4-ylmethylamino)-N-(4-(trifluo...)
Affinity DataIC50:  310nMAssay Description:Inhibition of VEGFR2 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201365(1-methyl-4-(pyridin-4-ylmethylamino)-N-(4-(trifluo...)
Affinity DataIC50:  280nMAssay Description:Inhibition of VEGFR1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50201365(1-methyl-4-(pyridin-4-ylmethylamino)-N-(4-(trifluo...)
Affinity DataIC50:  130nMAssay Description:Inhibition of VEGFR2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed