BDBM50201901 2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-carboxylicacid::CHEMBL218583

SMILES OC(=O)c1c(O)c(nc2c(cccc12)-c1ccccc1)-c1ccc(Cl)cc1

InChI Key InChIKey=OXHYIGFIYVMDLI-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50201901   

TargetCytochrome P450 2A6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of human CYP2A6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50:  1.51E+5nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP-selectin glycoprotein ligand 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of P-selectin-mediated adhesion of HL60 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50:  1.46E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed