BDBM50203447 CHEMBL3913553

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(c3)-c3noc(n3)-c3ccncc3)cc2C(F)(F)F)CC1

InChI Key InChIKey=KYFQTTFAFVYBMD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203447   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50203447(CHEMBL3913553)
Affinity DataIC50:  27nMAssay Description:Inhibition of RET (unknown origin) using poly[Glu:Tyr] (4:1) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed