BDBM50204327 CHEMBL3906347

SMILES Cc1cc(C)c2c(n1)sn(CC(=O)N1CCN(CC1)c1cccc(Cl)c1)c2=O

InChI Key InChIKey=HSWXAELHSCLZBD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204327   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204327(CHEMBL3906347)
Affinity DataIC50:  3.74E+5nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204327(CHEMBL3906347)
Affinity DataIC50:  6.05E+5nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204327(CHEMBL3906347)
Affinity DataIC50:  3.75E+5nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204327(CHEMBL3906347)
Affinity DataIC50:  6.05E+5nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed