BDBM50204364 CHEMBL3912571

SMILES Cc1cc(C)c2c(n1)sn(CN1CCN(CC1)c1ccccc1F)c2=O

InChI Key InChIKey=JEMDPIVDAGWLBO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50204364   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204364(CHEMBL3912571)
Affinity DataIC50:  1.56E+5nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204364(CHEMBL3912571)
Affinity DataIC50:  1.26E+6nMAssay Description:Inhibition of COX-2 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50204364(CHEMBL3912571)
Affinity DataIC50:  1.56E+5nMAssay Description:Inhibition of COX-1 (unknown origin) using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition in presence of TMPD b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed