BDBM50204871 (6-hydroxy-1H-indole-2-yl)-[4-(4-methoxy-benzyl)-piperidine-1-yl)]-methanone::CHEMBL374793

SMILES COc1ccc(CC2CCN(CC2)C(=O)c2cc3ccc(O)cc3[nH]2)cc1

InChI Key InChIKey=WRZWZVCAXXDIPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204871   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204871((6-hydroxy-1H-indole-2-yl)-[4-(4-methoxy-benzyl)-p...)
Affinity DataIC50:  17nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204871((6-hydroxy-1H-indole-2-yl)-[4-(4-methoxy-benzyl)-p...)
Affinity DataIC50:  80nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed