BDBM50204901 6-(4-benzylpiperidin-1-carbonyl)-1,5-dihydro-oxazolo[4,5-f]indol-2-one::CHEMBL374011

SMILES O=C(N1CCC(Cc2ccccc2)CC1)c1cc2cc3[nH]c(=O)oc3cc2[nH]1

InChI Key InChIKey=JAWRZCUFPBKZKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204901   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204901(6-(4-benzylpiperidin-1-carbonyl)-1,5-dihydro-oxazo...)
Affinity DataIC50:  23nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204901(6-(4-benzylpiperidin-1-carbonyl)-1,5-dihydro-oxazo...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed