BDBM50205093 CHEMBL428017::LRHYLNLLTRQRY-NH2

SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

InChI Key InChIKey=LZKBNKKHNKAGAE-ZQWBWPFKSA-N

Data  6 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50205093   

TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50205093(CHEMBL428017 | LRHYLNLLTRQRY-NH2)
Affinity DataKi:  5nMAssay Description:Binding affinity to NPYY2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50205093(CHEMBL428017 | LRHYLNLLTRQRY-NH2)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]PYY from human NPY2 receptor in KAN-TS cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50205093(CHEMBL428017 | LRHYLNLLTRQRY-NH2)
Affinity DataKi:  210nMAssay Description:Binding affinity to NPYY1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50205093(CHEMBL428017 | LRHYLNLLTRQRY-NH2)
Affinity DataKi:  210nMAssay Description:Displacement of [125I]PYY from human NPY1 receptor in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50205093(CHEMBL428017 | LRHYLNLLTRQRY-NH2)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]PYY from human NPY5 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50205093(CHEMBL428017 | LRHYLNLLTRQRY-NH2)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to NPYY5 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50205093(CHEMBL428017 | LRHYLNLLTRQRY-NH2)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human NPY2 receptor in KAN-TS cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50205093(CHEMBL428017 | LRHYLNLLTRQRY-NH2)
Affinity DataIC50:  3.90nMAssay Description:Agonist activity at neuropeptide Y Y2 receptor in human SMS-KAN cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50205093(CHEMBL428017 | LRHYLNLLTRQRY-NH2)
Affinity DataEC50:  6nMAssay Description:Agonist activity at NPYY2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed