BDBM50207362 CHEMBL3977870

SMILES CN1Cc2ccncc2N(C\C=C\c2cc(Nc3ncc(c1n3)C(F)(F)F)ccc2N1CCOCC1)S(C)(=O)=O

InChI Key InChIKey=SQSRYKIYYZPXLV-ONEGZZNKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207362   

TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207362(CHEMBL3977870)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207362(CHEMBL3977870)
Affinity DataIC50:  14nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed