BDBM50207478 CHEMBL223572::N-{4-[3-amino-7-(4-morpholinylmethyl)-1H-indazol-4-yl]phenyl}-N'-(3-methylphenyl)urea

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2ccc(CN3CCOCC3)c3[nH]nc(N)c23)c1

InChI Key InChIKey=TWVXVSDWFBDEBO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50207478   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207478(CHEMBL223572 | N-{4-[3-amino-7-(4-morpholinylmethy...)
Affinity DataIC50:  450nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207478(CHEMBL223572 | N-{4-[3-amino-7-(4-morpholinylmethy...)
Affinity DataIC50:  390nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207478(CHEMBL223572 | N-{4-[3-amino-7-(4-morpholinylmethy...)
Affinity DataIC50:  400nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed