BDBM50207508 CHEMBL219999::N-{4-[3-amino-1-(2-hydroxyethyl)-1H-indazol-4-yl]phenyl}-N'-(3-methylphenyl)urea

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3n(CCO)nc(N)c23)c1

InChI Key InChIKey=GRWZZLSYMYWWDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207508   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207508(CHEMBL219999 | N-{4-[3-amino-1-(2-hydroxyethyl)-1H...)
Affinity DataIC50:  600nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207508(CHEMBL219999 | N-{4-[3-amino-1-(2-hydroxyethyl)-1H...)
Affinity DataIC50:  270nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed