BDBM50207673 CHEMBL246259::N-(1-(2-methoxy-4-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)benzyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide

SMILES COc1cc(ccc1CN1CCC(CC1)NC(=O)c1cc(=O)c2ccc(F)cc2o1)C(=O)NCCN1CCCC1

InChI Key InChIKey=DMGSWCYGFARROW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50207673   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207673(CHEMBL246259 | N-(1-(2-methoxy-4-((2-(pyrrolidin-1...)
Affinity DataIC50:  270nMAssay Description:Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207673(CHEMBL246259 | N-(1-(2-methoxy-4-((2-(pyrrolidin-1...)
Affinity DataIC50:  26nMAssay Description:Displacement of [125I]MCH from MCHR1 expressed in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207673(CHEMBL246259 | N-(1-(2-methoxy-4-((2-(pyrrolidin-1...)
Affinity DataIC50:  6.60E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed