BDBM50208314 CHEMBL3884788

SMILES FC(F)Oc1ccc(cc1OCC1CC1)C(=O)Nc1ccccc1Cl

InChI Key InChIKey=FXJNCIZGQFVQLF-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50208314   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50:  501nMAssay Description:Inhibition of full length human PDE4C1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50:  170nMAssay Description:Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE9A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE5A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE10A2 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE2A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50:  39nMAssay Description:Inhibition of full length human PDE4D7 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50:  166nMAssay Description:Inhibition of full length human PDE4B1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE6C using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE8A1 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE11A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE1A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE3B using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50:  126nMAssay Description:Inhibition of full length human PDE4A4 using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50208314(CHEMBL3884788)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE7A using FAM-3',5'-cAMP as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed