BDBM50208589 CHEMBL3884848

SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(C)c3)n2)cc1C

InChI Key InChIKey=LJASUVQOUSTVGF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208589   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50208589(CHEMBL3884848)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human JAK3 using poly (Glu:Tyr) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50208589(CHEMBL3884848)
Affinity DataIC50:  50nMAssay Description:Inhibition of human JAK2 using poly (Glu:Tyr) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50208589(CHEMBL3884848)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of human EGFR using poly (Glu:Tyr) as substrate measured for 1.5 hrs by oregon green 488 dye-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed