BDBM50208592 CHEMBL3883652

SMILES CN1CCN(CC1)c1ccc(Nc2nccc(Nc3cccc(C)c3)n2)cc1

InChI Key InChIKey=NUIFHMPTQLPLND-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208592   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50208592(CHEMBL3883652)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human EGFR using poly (Glu:Tyr) as substrate measured for 1.5 hrs by oregon green 488 dye-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50208592(CHEMBL3883652)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human JAK3 using poly (Glu:Tyr) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50208592(CHEMBL3883652)
Affinity DataIC50:  140nMAssay Description:Inhibition of human JAK2 using poly (Glu:Tyr) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed