BDBM50209349 CHEMBL396287::N-[3-(4-{4-[1-(3-Chloro-benzoyl)-piperidin-4-yloxy]-3-methyl-phenylamino}-quinazolin-6-yl)-prop-2-ynyl]-2-methoxy-acetamide

SMILES COCC(=O)NCC#Cc1ccc2ncnc(Nc3ccc(OC4CCN(CC4)C(=O)c4cccc(Cl)c4)c(C)c3)c2c1

InChI Key InChIKey=UBLCGEZIPYNWGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209349   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209349(CHEMBL396287 | N-[3-(4-{4-[1-(3-Chloro-benzoyl)-pi...)
Affinity DataIC50:  75nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209349(CHEMBL396287 | N-[3-(4-{4-[1-(3-Chloro-benzoyl)-pi...)
Affinity DataIC50:  210nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed