BDBM50210526 (1S,2R,5R)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-2-(2,4,5-trifluorophenyl)cyclohexanamine::CHEMBL232191

SMILES N[C@H]1C[C@@H](CCC1c1cc(F)c(F)cc1F)N1CCn2c(C1)nnc2C(F)(F)F

InChI Key InChIKey=CNKRZILQBKJWDS-SXWOTNNOSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50210526   

TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210526((1S,2R,5R)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210526((1S,2R,5R)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210526((1S,2R,5R)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210526((1S,2R,5R)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210526((1S,2R,5R)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50:  140nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed