BDBM50211072 CHEMBL3974488

SMILES Br.CC(C)(C)c1ccc(OCCCON2C(N)=NC(N)=NC22CCOCC2)cc1

InChI Key InChIKey=HDCSYSXGGYVMJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50211072   

TargetDihydrofolate reductase(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50211072(CHEMBL3974488)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured every 5 sec over 6 mins in presence of NADPH by UV-Visible spectrophotometric me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed