BDBM50211349 CHEMBL232592::N-((1s,4s)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-2-nitrobenzenesulfonamide

SMILES CC(C)Oc1ccccc1N1CCN(CC1)[C@@H]1CC[C@@H](CC1)NS(=O)(=O)c1ccccc1[N+]([O-])=O

InChI Key InChIKey=HEEKUWDLPPDKMK-OYRHEFFESA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211349   

TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50211349(CHEMBL232592 | N-((1s,4s)-4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to human cloned adrenergic alpha1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50211349(CHEMBL232592 | N-((1s,4s)-4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity to human cloned adrenergic alpha1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50211349(CHEMBL232592 | N-((1s,4s)-4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  51nMAssay Description:Binding affinity to human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50211349(CHEMBL232592 | N-((1s,4s)-4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  201nMAssay Description:Binding affinity to human cloned adrenergic alpha1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed