BDBM50211481 CHEMBL226814::benzo[1,3]dioxole-5-carboxylic acid (3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a,6,10,10a,10b-decahydro-1-oxa-7-thia-9-aza-dicyclopenta[a,g]naphthalen-8-yl)-amide

SMILES CC1C2CCC3(C)Cc4sc(NC(=O)c5ccc6OCOc6c5)nc4C(C)C3C2OC1=O

InChI Key InChIKey=AEFCHFDXZTVNCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211481   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211481(CHEMBL226814 | benzo[1,3]dioxole-5-carboxylic acid...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211481(CHEMBL226814 | benzo[1,3]dioxole-5-carboxylic acid...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed