BDBM50211485 2-(2-methoxy-phenyl)-N-(3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a,6,10,10a,10b-decahydro-1-oxa-7-thia-9-aza-dicyclopenta[a,g]naphthalen-8-yl)-acetamide::CHEMBL389289

SMILES COc1ccccc1CC(=O)Nc1nc2C(C)C3C4OC(=O)C(C)C4CCC3(C)Cc2s1

InChI Key InChIKey=OYLCCQPMKOSHSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211485   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211485(2-(2-methoxy-phenyl)-N-(3,5a,10-trimethyl-2-oxo-2,...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211485(2-(2-methoxy-phenyl)-N-(3,5a,10-trimethyl-2-oxo-2,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed