BDBM50211486 4-methyl-[1,2,3]thiadiazole-5-carboxylic acid (3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a,6,10,10a,10b-decahydro-1-oxa-7-thia-9-aza-dicyclopenta[a,g]naphthalen-8-yl)-amide::CHEMBL375910
SMILES CC1C2CCC3(C)Cc4sc(NC(=O)c5snnc5C)nc4C(C)C3C2OC1=O
InChI Key InChIKey=XLAGJGYXKBDIQM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50211486
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT
Curated by ChEMBL
Johann Wolfgang Goethe-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT
Curated by ChEMBL
Johann Wolfgang Goethe-UniversitäT
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair