BDBM50211489 2-(7-(2-(dimethylamino)ethoxy)-5,8-dimethyl-1,2,3,4-tetrahydronaphthalen-2-yl)-N-(thiazol-2-yl)propanamide::CHEMBL227354

SMILES CC(C1CCc2c(C)cc(OCCN(C)C)c(C)c2C1)C(=O)Nc1nccs1

InChI Key InChIKey=ZFUJXRWIEDOTHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211489   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211489(2-(7-(2-(dimethylamino)ethoxy)-5,8-dimethyl-1,2,3,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50211489(2-(7-(2-(dimethylamino)ethoxy)-5,8-dimethyl-1,2,3,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed