BDBM50211988 CHEMBL393001::N-(4-chlorophenyl)-1-(2-(pyridin-4-yl)ethyl)-1H-tetrazole-5-carboxamide

SMILES Clc1ccc(NC(=O)c2nnnn2CCc2ccncc2)cc1

InChI Key InChIKey=LDKBYKZJBJZJKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211988   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211988(CHEMBL393001 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)
Affinity DataIC50:  890nMAssay Description:Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211988(CHEMBL393001 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211988(CHEMBL393001 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)
Affinity DataIC50:  640nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed