BDBM50212022 4-(5-cyano-2-(4-(2-hydroxyethyl)phenylamino)pyrimidin-4-yl)benzenesulfonamide::CHEMBL234275

SMILES NS(=O)(=O)c1ccc(cc1)-c1nc(Nc2ccc(CCO)cc2)ncc1C#N

InChI Key InChIKey=JLROWURZPMPBKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212022   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50212022(4-(5-cyano-2-(4-(2-hydroxyethyl)phenylamino)pyrimi...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50212022(4-(5-cyano-2-(4-(2-hydroxyethyl)phenylamino)pyrimi...)
Affinity DataIC50:  200nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed