BDBM50212030 4-phenyl-2-(4-(2-(pyrrolidin-1-yl)ethyl)phenylamino)pyrimidine-5-carbonitrile::CHEMBL233455

SMILES N#Cc1cnc(Nc2ccc(CCN3CCCC3)cc2)nc1-c1ccccc1

InChI Key InChIKey=WQTAQMLQEQKKFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212030   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50212030(4-phenyl-2-(4-(2-(pyrrolidin-1-yl)ethyl)phenylamin...)
Affinity DataIC50:  110nMAssay Description:Inhibition of VEGFR2 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50212030(4-phenyl-2-(4-(2-(pyrrolidin-1-yl)ethyl)phenylamin...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of CDK1 activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed