BDBM50212249 CHEMBL3900422

SMILES CC(C)[C@@H](N(CCNC(=O)c1ccccc1)S(=O)(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO

InChI Key InChIKey=QHCDOFQMQJCFGF-XMMPIXPASA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50212249   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50212249(CHEMBL3900422)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of p-aminophenylmercuric acetate activated recombinant human MMP-9 expressed in CHO cells pretreated for 4 hrs followed by Mca-Lys-Pro-Leu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50212249(CHEMBL3900422)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of p-aminophenylmercuric acetate activated recombinant human MMP-2 expressed in CHO cells pretreated for 4 hrs followed by Mca-Lys-Pro-Leu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50212249(CHEMBL3900422)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain pretreated for 4 hrs followed by Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 fluorogenic sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50212249(CHEMBL3900422)
Affinity DataIC50:  13nMAssay Description:Inhibition of p-aminophenylmercuric acetate activated human rheumatoid synovial fibroblast MMP-1 pretreated for 4 hrs followed by Mca-Lys-Pro-Leu-Gly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed