BDBM50214943 10-methoxy-2,2,4-trimethyl-5-[1-o-tolyl-meth-(Z)-ylidene]-2,4a,5,12a-tetrahydro-1H-6-oxa-1-aza-chrysen-9-ol::CHEMBL401433
SMILES COc1c(O)ccc2O\C(=C/c3ccccc3C)C3=C(C=CC4NC(C)(C)C=C(C)C34)c12
InChI Key InChIKey=LPMXWEDLVSWNIP-UCQKPKSFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50214943
Affinity DataKi: 1.70nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40nMAssay Description:Agonist activity at GR by GRE activation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Activity at GR assessed as repression of TNFalpha and IL 1beta induced E-selectin responseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Antagonist activity at GR assessed as inhibition of dexamethasone-induced GRE activationMore data for this Ligand-Target Pair