BDBM50214945 10-methoxy-2,2,4-trimethyl-5-[1-p-tolyl-meth-(Z)-ylidene]-2,4a,5,12a-tetrahydro-1H-6-oxa-1-aza-chrysen-9-ol::CHEMBL231976
SMILES COc1c(O)ccc2O\C(=C/c3ccc(C)cc3)C3=C(C=CC4NC(C)(C)C=C(C)C34)c12
InChI Key InChIKey=ZVTZHOAJVOFUEH-UCQKPKSFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50214945
Affinity DataKi: 1.90nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Agonist activity at GR by GRE activation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at GR assessed as inhibition of dexamethasone-induced GRE activationMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Activity at GR assessed as repression of TNFalpha and IL 1beta induced E-selectin responseMore data for this Ligand-Target Pair