BDBM50215340 (3R,4R)-1-(pyrazin-2-yl)-4-(2,4,5-trifluorophenyl)piperidin-3-aminium 2,2,2-trifluoroacetate::CHEMBL230985

SMILES [NH3+][C@H]1CN(CC[C@@H]1c1cc(F)c(F)cc1F)c1cnccn1

InChI Key InChIKey=AZXSMSNEBXEWAJ-OTYXRUKQSA-O

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50215340   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215340((3R,4R)-1-(pyrazin-2-yl)-4-(2,4,5-trifluorophenyl)...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215340((3R,4R)-1-(pyrazin-2-yl)-4-(2,4,5-trifluorophenyl)...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215340((3R,4R)-1-(pyrazin-2-yl)-4-(2,4,5-trifluorophenyl)...)
Affinity DataIC50:  82nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50215340((3R,4R)-1-(pyrazin-2-yl)-4-(2,4,5-trifluorophenyl)...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed