BDBM50215449 5-methyl-3-(2-(3-(trifluoromethyl)phenyl)ethynyl)-1,2,4-triazine::CHEMBL227202
SMILES Cc1cnnc(n1)C#Cc1cccc(c1)C(F)(F)F
InChI Key InChIKey=GSSJQBLTGAEIQZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50215449
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Antagonist activity at human mGluR5 receptor expressed in CHOK1 cells assessed as inhibition of glutamate-mediated internal calcium mobilizationMore data for this Ligand-Target Pair