BDBM50215497 5-methoxy-9,12-diazatetracyclo[10.3.1.0^{2,10}.0^{3,8}]hexadeca-2(10),3,5,7-tetraene-11-carboxylic acid::CHEMBL394124

SMILES COc1ccc2[nH]c3C(N4CCCC(C4)c3c2c1)C(O)=O

InChI Key InChIKey=BDRAYCVSLZSFNY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215497   

TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215497(5-methoxy-9,12-diazatetracyclo[10.3.1.0^{2,10}.0^{...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of PRAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215497(5-methoxy-9,12-diazatetracyclo[10.3.1.0^{2,10}.0^{...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215497(5-methoxy-9,12-diazatetracyclo[10.3.1.0^{2,10}.0^{...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of MK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed