BDBM50216241 (6S,10bR)-6-(4-(1H-imidazol-1-yl)phenyl)-9-(3-morpholinopropoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline::CHEMBL246913

SMILES C(COc1ccc2[C@@H](CN3CCC[C@@H]3c2c1)c1ccc(cc1)-n1ccnc1)CN1CCOCC1

InChI Key InChIKey=SURMDNBXOGRWFS-WUFINQPMSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50216241   

TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50216241((6S,10bR)-6-(4-(1H-imidazol-1-yl)phenyl)-9-(3-morp...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50216241((6S,10bR)-6-(4-(1H-imidazol-1-yl)phenyl)-9-(3-morp...)
Affinity DataKi:  6.70nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50216241((6S,10bR)-6-(4-(1H-imidazol-1-yl)phenyl)-9-(3-morp...)
Affinity DataKi:  16.7nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed