BDBM50216692 2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(quinolin-8-yl)acrylamide::CHEMBL226026

SMILES Clc1ccc(Cl)c(c1)-c1ccc(\C=C(/C#N)C(=O)Nc2cccc3cccnc23)o1

InChI Key InChIKey=WRDKBSLEHFRKGG-RVDMUPIBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50216692   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50216692(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant SIRT2 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50216692(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant SIRT3 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50216692(2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(qu...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant SIRT1 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed