BDBM50217482 CHEMBL236516::tert-butyl 2-((3S,7S)-2-oxo-3-(4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxamido)-7-phenylazepan-1-yl)acetate

SMILES CC(C)(C)OC(=O)CN1[C@@H](CCC[C@H](NC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)C1=O)c1ccccc1

InChI Key InChIKey=FFKJRZZAQCOLKI-SVBPBHIXSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217482   

TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50217482(CHEMBL236516 | tert-butyl 2-((3S,7S)-2-oxo-3-(4-(2...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50217482(CHEMBL236516 | tert-butyl 2-((3S,7S)-2-oxo-3-(4-(2...)
Affinity DataIC50:  2.12E+3nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50217482(CHEMBL236516 | tert-butyl 2-((3S,7S)-2-oxo-3-(4-(2...)
Affinity DataIC50:  471nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed