BDBM50217490 CHEMBL428547::N-((3R,7R)-1-(cyclopropylmethyl)-2-oxo-7-phenylazepan-3-yl)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxamide
SMILES O=C(N[C@@H]1CCC[C@@H](N(CC2CC2)C1=O)c1ccccc1)N1CCC(CC1)N1Cc2ccccc2NC1=O
InChI Key InChIKey=PORPTQSGGWNOJX-KAYWLYCHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50217490
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 689nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 408nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair