BDBM50217735 CHEMBL236002::N-(2-bromo-4,5-dimethoxycinnamyl)-4-(2-(4-hydroxybenzyl)-1H-indol-3-yl)-N-(4-((4-aminocyclohexyl)methyl)cyclohexyl)butanamide

SMILES COc1cc(Br)c(\C=C\CN(C2CCC(CC3CCC(N)CC3)CC2)C(=O)CCCc2c(Cc3ccc(O)cc3)[nH]c3ccccc23)cc1OC

InChI Key InChIKey=GPQMZEWRRBFAKD-VOTSOKGWSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50217735   

TargetMelanocyte-stimulating hormone receptor(Mus musculus)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217735(CHEMBL236002 | N-(2-bromo-4,5-dimethoxycinnamyl)-4...)
Affinity DataKi:  940nMAssay Description:Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217735(CHEMBL236002 | N-(2-bromo-4,5-dimethoxycinnamyl)-4...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217735(CHEMBL236002 | N-(2-bromo-4,5-dimethoxycinnamyl)-4...)
Affinity DataKi:  1.80E+4nMAssay Description:Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50217735(CHEMBL236002 | N-(2-bromo-4,5-dimethoxycinnamyl)-4...)
Affinity DataKi:  9.40E+4nMAssay Description:Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed