BDBM50217918 3-(2-fluoro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hpyrrolo[2,3-b]pyridine::CHEMBL240922

SMILES Fc1ccccc1S(=O)(=O)c1cn(C2CCNC2)c2ncccc12

InChI Key InChIKey=VNCIUCWRVXNSTB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217918   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217918(3-(2-fluoro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217918(3-(2-fluoro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...)
Affinity DataKi:  2nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217918(3-(2-fluoro-benzenesulfonyl)-1-pyrrolidin-3-yl-1Hp...)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed