BDBM50218248 CHEMBL69776

SMILES COc1ccc(C(=O)Nc2ccccc2Cl)c2cc(oc12)C(C)=O

InChI Key InChIKey=MPXKKKYXZROOTK-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218248   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience

Curated by ChEMBL

LigandBDBM50218248(CHEMBL69776)Copy SMILESCopy InChI

Affinity DataIC50:  248nMAssay Description:Inhibition of rolipram binding to rat brain tissueMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))TBA

LigandBDBM50218248(CHEMBL69776)Copy SMILESCopy InChI

Affinity DataIC50:  54nMAssay Description:Inhibition of PDE4 in Homo sapiens (human) U937 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOI

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))TBA

LigandBDBM50218248(CHEMBL69776)Copy SMILESCopy InChI

Affinity DataIC50:  54nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI