BDBM50218253 CHEMBL70090

SMILES COc1ccc(C(=O)Nc2cccnc2Cl)c2cc(oc12)C(C)=O

InChI Key InChIKey=QHCGTIDBZVWMRI-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218253   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience

Curated by ChEMBL

LigandBDBM50218253(CHEMBL70090)Copy SMILESCopy InChI

Affinity DataIC50:  199nMAssay Description:Inhibition of rolipram binding in rat brain tissueMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))TBA

LigandBDBM50218253(CHEMBL70090)Copy SMILESCopy InChI

Affinity DataIC50:  875nMAssay Description:Inhibition of PDE4 in Homo sapiens (human) U937 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails Article
Copy BDB DOI

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))TBA

LigandBDBM50218253(CHEMBL70090)Copy SMILESCopy InChI

Affinity DataIC50:  875nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI