BDBM50218285 5-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)benzamido)-tetrahydrofuran-3-yl)thiophene-2-carboxamide::CHEMBL237705

SMILES Clc1ccc(s1)C(=O)N[C@@H]1COC[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O

InChI Key InChIKey=YGGDWBZARHRUFI-JKSUJKDBSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50218285   

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218285(5-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218285(5-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >1.10E+4nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218285(5-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >1.10E+4nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218285(5-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >1.20E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218285(5-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >1.40E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218285(5-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human activated protein CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218285(5-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >2.10E+4nMAssay Description:Inhibition of human tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218285(5-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >2.20E+4nMAssay Description:Inhibition of human PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed