BDBM50219268 CHEMBL399298::tert-butyl (R)-1-(5-(aminomethyl)-2-(8-methoxy-2-(trifluoromethyl)quinolin-5-yl)oxazole-4-carbonyl)pyrrolidin-3-ylcarbamate

SMILES COc1ccc(-c2nc(C(=O)N3CC[C@H](C3)NC(=O)OC(C)(C)C)c(CN)o2)c2ccc(nc12)C(F)(F)F

InChI Key InChIKey=BJMBBXFCGSCMCV-CYBMUJFWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219268   

TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219268(CHEMBL399298 | tert-butyl (R)-1-(5-(aminomethyl)-2...)
Affinity DataIC50:  820nMAssay Description:Inhibition of PDE11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219268(CHEMBL399298 | tert-butyl (R)-1-(5-(aminomethyl)-2...)
Affinity DataIC50:  130nMAssay Description:Inhibition of PDE10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50219268(CHEMBL399298 | tert-butyl (R)-1-(5-(aminomethyl)-2...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed