BDBM50220725 CHEMBL237101::N-((1r,4r)-4-(4-hydroxyphenyl)cyclohexyl)-3-(5-methylthiazol-2-yl)propanamide

SMILES Cc1cnc(CCC(=O)N[C@H]2CC[C@@H](CC2)c2ccc(O)cc2)s1

InChI Key InChIKey=YRDBOFSDLLYYQB-KOMQPUFPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220725   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220725(CHEMBL237101 | N-((1r,4r)-4-(4-hydroxyphenyl)cyclo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human HERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220725(CHEMBL237101 | N-((1r,4r)-4-(4-hydroxyphenyl)cyclo...)
Affinity DataIC50:  96nMAssay Description:Displacement of [3H]CP101,606 from NR2B in rat forebrain P2 membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed