BDBM50221521 7-methoxy-6-(2-morpholinoethoxy)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile::CHEMBL401054
SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OCCN1CCOCC1
InChI Key InChIKey=SIMNHPGTUXYIRW-NZQKXSOJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50221521
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
Affinity DataKi: 64nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of Flt1More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
Affinity DataIC50: 405nMAssay Description:Inhibition of human EGFR autophosphorylation in A431 cellsMore data for this Ligand-Target Pair