BDBM50221523 7-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile::CHEMBL248045
SMILES COc1ccc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2c1)C#N
InChI Key InChIKey=SRISCUOQTDYYHZ-PKOBYXMFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50221523
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
Affinity DataKi: 180nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of Flt1More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tanabe Research Laboratories Usa
Curated by ChEMBL
Tanabe Research Laboratories Usa
Curated by ChEMBL
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of human EGFR autophosphorylation in A431 cellsMore data for this Ligand-Target Pair