BDBM50221952 (R)-(5-chloro-6-(3-methyl-4-(5-(4-(trifluoromethyl)phenyl)-4-(3,4,5-trifluorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)pyridin-3-yl)methanol::CHEMBL251094

SMILES C[C@@H]1CN(CCN1c1nc(c([nH]1)-c1ccc(cc1)C(F)(F)F)-c1cc(F)c(F)c(F)c1)c1ncc(CO)cc1Cl

InChI Key InChIKey=XDNXJYNTLHMFAF-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221952   

TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50221952((R)-(5-chloro-6-(3-methyl-4-(5-(4-(trifluoromethyl...)
Affinity DataIC50:  4nMpH: 5.0Assay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of acid-induced calcium influx at pH 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50221952((R)-(5-chloro-6-(3-methyl-4-(5-(4-(trifluoromethyl...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of capsaicin-induced calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed