BDBM50222493 (R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-5-yloxy)propan-2-yl)-2-hydroxy-N-methylacetamide::CHEMBL250130

SMILES C[C@H](COc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)N(C)C(=O)CO

InChI Key InChIKey=HXMKNGQXLJHQDQ-QGZVFWFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50222493   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222493((R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222493((R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed